Lee was a very successful physician, even attending Frederick, Prince of Wales at one point in his career. He wrote occassional verses while at University and published an oration as Harveian orator in 1736. He died wealthy enough to bequeath funds in his will to build an anatomy school at Christ Church, which was completed at a cost of £1200. In addition, Lee left £140 p.a. for a university readership in anatomy (to which appointments are still made).