A clergyman, Broome published two sermons, but he is best known for his translations of Homer. He collaborated on Pope's translation of The Odyssey along with Elijah Fenton, but Pope's reluctance to acknowledge the full extent of Broome's contributions caused strained relations between the two for the rest of their lives. Pope attacked Broome explicitly in the Peri Bathous (1727) and in the Dunciad (1728). Broome published one collected volume of poetry.