Introduction to AZT | The Chemistry of AZT| Side Effects| Pregnancy| An Anything But American Virus| Opposing Views| How AZT Changed History|
- Nearly doubled the life expectancy for persons with AIDS
- Can reduce maternal transmission of AIDS during pregnancy by 2/3
- Too toxic for cancer in 1964 but worked 20 years later with antiviral therapy
- March 1987 “The world of clinical research was turned upside down” (National
Academy of Sciences) when the FDA approved AZT after phase one instead of the usual phase 3
- $10,000 annually-one of the most expensive drugs in history
