Introductionto Estradiol, Definition and Structure, Estradiol’s Effect on History: Medicinal Purposes, Estradiol’s Effect on History: Therapeutic Purposes, History’s Effect on Estradiol
Definition:
- Estradiol is a sex hormone present in both females and males.
- Estradiol is one of the three naturally occuring estrogens in females, along with estriol and estrone
- It is present in women from puberty until menopause
- It is essential for the reproductive system, as well as for sexual reasons
- Affects many of the body’s major systems
- Synthetic estradiol is used in the pill, for hormone replacement therapy in transsexuals, and for postmenopausal women
- Estradiol is derived from cholesterol which is converted into androstenedione. Androstendione is then converted to testosterone which in turn is converted to estradiol
Structure
- Conversion from Testosterone to Estradiol:
