The Role of Chemistry in History

The Role of Chemistry in History header image 2


April 29th, 2008 · No Comments ·

Introduction | History | How It Works

Uses | Typhoid Fever | Side Effects

Synthetic Production | U.S. and the West



In 1947, professor of plant pathology at the University of Illinois David Gottlieb isolated a strain of Streptomyces (a bacteria found in soil), from which Chloramphenicol was developed.

Chloramphenicol was introduced into clinical use in 1948.

Chloramphenicol was seen, upon its discovery, as a near-perfect drug.
• It could be given orally, and at home
• Because of it high pH, it is able to penetrate purulent material (material containing pus), and through cell membranes to parasites and into organs that other antibiotics could not reach

Tags: Chloramphenicol